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KMID : 0360220080490010071
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Journal of the Korean Ophthalmological Society
2008 Volume.49 No. 1 p.71 ~ p.80
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The Combined Effect of Subtenon Triamcinolone Injection and Panretinal Photocoagulation on Diabetic Retinopathy
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Kang Seung-Bum
Park Young-Hoon
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Abstract
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Purpose : To investigate the result of posterior sub-tenon triamcinolone acetonide injection combined with
panretinal photocoagulation (PRP) in patients with diabetic retinopathy.
Methods : A prospective study was performed on patients with diabetic retinopathy who required PRP. The
study group consisted of 12 patients (12 eyes) of diabetic retinopathy without clinically significant macular
edema (CSME) and 13 patients (13 eyes) with CSME. All patients were injected posteriorly with sub-tenon
triamcinolone acetonide (40 mg) one week before PRP. During a six-month follow-up, best-corrected visual
acuity, the development of macular edema, changes in fluorescein angiography, and related complications were
monitored.
Results : During a six-month follow-up, visual acuity was well preserved in patients with diabetic retinopathy
without CSME (12 eyes). Only one patient in this group experienced temporary macular edema at 3 months
after combined therapy. In the CSME group (13 eyes), the visual acuities of seven patients (53.8%) increased,
those of five patients (38.5%) remained same, and one patient’s visual acuity (7.7%) decreased in a study
period of six months. Fluorescein angiography showed that macular edema was resolved in most patients
except in one patient in whom macular edema remained for up to 6 months. Complications from combined
therapy occurred in two patients who showed slight and temporary increase of intraocular pressure.
Conclusion : Combined treatment with posterior sub-tenon triamcinolone acetonide injection and PRP may
provide benefits for patients with diabetic retinopathy who require urgent PRP by preventing exacerbation of
macular edema.
J Korean Ophthalmol Soc 49(1):71-80, 2008
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KEYWORD
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Panretinal photocoagulation, Posterior sub-tenon injection, Triamcinolone acetonide
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